No, none of the drugs that are used as antidepressants currently are not addictive. Approximately 10% of antidepressant treatment causes side effects that require immediate discontinuation of the drug. The symptoms are different for different patients, different severity and duration. This could be nausea and vomiting, chills, muscle aches, headache and diarrhea. The dose of drug causing unwanted symptoms are also different for different people.