This is a difficult question. Unfortunately, if a person has experienced depression, there is a substantial likelihood that he will survive it again. It is assumed that the risk of relapse of depression is about 50%. With two or more depressive episodes the probability of depression and its rate of occurrence increases as well. Therefore, the duration of medication is adjusted accordingly. Typically after the initial depression episode it is recommended at least six to nine months to continue treatment. If it is a repeated episodes, medication, lasts for several years.